| Abstract Detail
Thursday Afternoon Breeding and Variation Peleman, Johan [1], SØrensen, Anker [1], Buntjer, Jaap [1], Van Eijk, Michiel [1], Rouppe van der Voort, Jeroen [1]. Coming up soon: Breeding By Design. IN future variety development programs, we expect that the breeder will compose desired superior genotypes in silico, an approach which we have called ‘Breeding by DesignTM’. This will be feasible because for many agronomically important traits, we can determine the precise map position of the underlying genes, the interaction between those loci, and the allelic variation at these loci together with their phenotypic values. Subsequently, the desired genotypes can be generated using easy-to-assay molecular markers and breeding scheme designer software. The presentation will report on recent advances in molecular marker technology, such as CRoPSTM and Single Feature Polymorphisms (SFP), which provide opportunities to develop refined mapping strategies based on whole genome LD mapping using marker haplotypes. Complementary to this approach, an effective method for fine mapping QTL, called QIR analysis, will also be presented. The CRoPS technology is covered by patent applications owned by Keygene N.V.. Trademark registration has been filed for Breeding By Design and CRoPS. References BUNTJER, J. B., SORENSEN, A. P., PELEMAN J.D. Haplotype diversity: the link between statistical and biological association (Trends in Plant Science, vol. 10, nr.10, October 2005) PELEMAN, J.D., WYE, C., ZETHOF, J., SORENSEN, A., VERBAKEL, H., VAN OEVEREN, J., GERATS, T., ROUPPE VAN DER VOORT, J. ‘QTL Isogenic Recombination (QIR) analysis: A method for high resolution mapping of quantitative trait loci within a single population’ (Genetics, 171:1341-1352, November 2005) PELEMAN, J., ROUPPE VAN DER VOORT, J. Breeding by Design (Trends in Plant Science, vol.8, nr.7, 330-334, 2003)
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1 - Keygene N.V., Agro Business Park 90, Wageningen, 6708 PW, The Netherlands
Keywords:
CRoPS
Haplotypes.
Session: SOL07-1
Location: Ballroom AB/Monona Terrace
Date: Thursday, July 27th, 2006
Time: 1:30 PM
Abstract ID:40 |
