| Abstract Detail
Physiology Goyer, Aymeric [1], Hamm, Philip [2], Navarre, Roy [3]. Germplasm mining and metabolic engineering as strategies to boost folates in potato tubers. TETRAHYDROFOLATE, and its one carbon unit derivatives commonly named folates (vitamin B9), are essential micronutrients in the human diet. Folates are cofactors of one carbon units transfer reactions that are crucial for the DNA biosynthesis cycle and the methylation cycle. A deficiency of folates in the diet is associated with the risk of birth defects, vascular diseases, anemia, and some cancers. Worldwide current human intake is suboptimal, even in Western rich countries like the U.S. To decrease the rate of folate deficiency-associated diseases, folic acid fortification of grain products was fully implemented in 1998 in the U.S. An attractive alternative to food fortification and folic acid supplements is to enhance folate levels in plant foods (biofortification). Two approaches are being used to boost folate in potato tubers: (1) utilize germplasm mining to identify varieties or wild species with enhanced folate levels and determine what factors are responsible for this variability; (2) a transgenic approach to alter folate levels by manipulating genes that regulate folate concentration in potato tubers.
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1 - Oregon State University, 24106 N. Bunn Road, Prosser, Wa, 99350, USA
2 - Oregon State University, Botany & Plant Pathology, PO Box 105, Hermiston, OR, 97838, USA
3 - USDA-Agricultural Research Service, 24106 N. Bunn Road, Prosser, Wa, 99350, USA
Keywords:
folic acid.
Session: Poster-22
Location: Ballroom CD/Monona Terrace
Date: Tuesday, July 25th, 2006
Time: 8:00 AM
Abstract ID:382 |
